Farbstudie Quadrate by Wassily Kandinsky

The Blackwell Lab located in the Chemistry Department at the University of Wisconsin – Madison works at the interface of chemistry and biology.

See Research for an overview of our group's current research directions and Publications for work we've already published.

Image: Farbstudie Quadrate by Wassily Kandinsky

In partnership with Sigma-Aldrich, several of the lab's lead modulators of LuxR-type quorum sensing receptors are now available for sale!

News & Updates

  • November 18, 2015

    Several of our potent quorum sensing modulators are now available for purchase via Sigma-Aldrich! Check out the inventory here!

  • November 03, 2015

    Congrats, Matt O'Reilly! His paper titled, "Structure-Based Design and Biological Evaluation of Triphenyl Scaffold Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor" was accepted to ACS Infectious Diseases!

  • November 03, 2015

    Three new chemistry grad students joined the lab this week: Daniel Manson, Matt Styles, and Joe Manulik! Welcome, guys!

  • October 22, 2015

    Congratulations, Joe Moore, Frank, Michael, and Kayleigh! They had a paper accepted to JACS titled, "A comparative analysis of synthetic quorum sensing modulators in Pseudomonas aeruginosa: New insights into mechanism, active efflux susceptibility, phenotypic response, and next-generation ligand design"!

  • September 23, 2015

    Way to go, Yftah! His second paper on his structural NMR studies titled, "Characterization of Structural Elements in Native Autoinducing Peptides and Non-Native Analogues that Permit the Differential Modulation of AgrC-type Quorum Sensing Receptors in Staphylococcus aureus" was published today in Organic & Biomolecular Chemistry!